What Is PDGF and How Can It Improve Your Skin?
- Elsie Calo
- Aug 10
- 2 min read
If you’re looking for a way to boost skin rejuvenation and get more out of treatments like microneedling or RF microneedling, PDGF may be worth knowing about.
What Is PDGF?
PDGF stands for Platelet-Derived Growth Factor. It is a naturally occurring growth factor involved in your body’s healing and tissue-repair process.
In aesthetics, purified recombinant PDGF can be applied after certain skin treatments to support the skin’s natural regenerative response.
What Are the Benefits of PDGF?
PDGF helps support the processes involved in skin repair and regeneration. When incorporated into a skin-rejuvenation treatment plan, potential benefits include:
Supporting collagen production and skin renewal
Improving overall skin quality and texture
Helping soften the appearance of fine lines
Supporting recovery after certain aesthetic treatments
Enhancing the results of microneedling and RF microneedling
Recent clinical research found that applying pure PDGF after RF microneedling produced greater improvements in facial skin quality than RF microneedling followed by standard post-treatment care alone.
PDGF + Microneedling
Microneedling and RF microneedling create controlled micro-injuries that trigger the skin’s natural repair process. Adding PDGF after treatment provides additional regenerative signals during this important healing period.
Think of microneedling as starting the repair process and PDGF as providing additional support to help your skin make the most of it.
Is PDGF the Same as PRP or PRF?
No. PRP and PRF are created from a sample of your own blood and contain a mixture of platelets and naturally occurring growth factors.
Purified recombinant PDGF provides a standardized growth factor without requiring a blood draw. This can make it an attractive regenerative option for patients who want to enhance their skin-rejuvenation treatments.
Is PDGF Right for You?
PDGF may be a great addition for patients looking to improve skin texture, fine lines, signs of aging, and overall skin quality—especially when combined with treatments designed to stimulate collagen.
At Healthy Glow Medical in Orlando, we can determine whether PDGF should be incorporated into your personalized skin-rejuvenation plan.
Healthy Glow Med Spa
1579 Lake Baldwin Ln, Suite A., Orlando, FL 32814
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